APOE and cortical superficial siderosis in CAA
نویسندگان
چکیده
منابع مشابه
Superficial cortical siderosis.
Cerebrovascular deposition of amyloid (cerebral amyloid angiopathy CAA) is most commonly recognized as a cause of spontaneous lobar intracerebral hemorrhage. On the basis of the noninvasive new MR imaging we would propose superficial cortical hemosiderosis and subarachnoid hemosiderosis as potentially useful new criteria to facilitate the diagnosis of CAA.
متن کاملCortical superficial siderosis, APOE genotype, and hemorrhage risk in cerebral amyloid angiopathy.
The deposition of Ab amyloid in the walls of cortical and leptomeningeal blood vessels characterizes cerebral amyloid angiopathy (CAA). Clinical presentation of CAA ranges from transient neurologic events to cognitive decline to symptomatic intracerebral hemorrhage (ICH). Radiologically, CAA can present with structural brain lesions (e.g., microbleeds, white matter hyperintensities, or microinf...
متن کاملSuperficial siderosis.
Case 1 An elderly patient presented with insidious onset of sensorineural hearing loss. The past history was unremarkable except for insidious onset of weakness of left lower limb. Physical examination revealed left hemiparesis with upgoing left plantar. Magnetic resonance imaging (MRI) of brain revealed a large flow void in the interpeduncular cistern suggestive of aneurysm arising from the to...
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BACKGROUND Superficial siderosis (SS) is caused by repeated or continuous bleeding into the subarachnoid space that results in iron from hemoglobin (hemosiderin) being deposited on the surface of the brain. Clinically, the condition is characterized by sensorineural deafness, ataxia, and pyramidal signs. However the mechanism of peripheral vestibular disturbance was not revealed. We show the ve...
متن کاملSuperficial siderosis in cerebral amyloid angiopathy
With great interest, we read the recent review article by Kumar entitled “Neuroimaging in Superficial Siderosis: An In-Depth Look,” published on-line ahead of print in the American Journal of Neuroradiology in September 2009. The author provides a thorough review of neuroimaging in superficial siderosis (SS) of the central nervous system and details important underlying causes of this phenomeno...
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ژورنال
عنوان ژورنال: Neurology
سال: 2019
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000007818